Concept
Risk Stratification
Future of Cancer Science | AACR Cancer Progress Report 2025 / Diagnosing Cancer and Predicting Metastases
"Liquid biopsies can also identify patients at the highest risk for cancer spread. In individuals with pancreatic cancer, detection of mutant KRAS ctDNA was strongly associated with metastatic tumors that were difficult to detect by conventional methods and poor survival outcomes, offering new insights into disease biology and aiding decisions about surgery and treatment intensity (1081)Leiting JL, et al. (2025) Ann Surg Oncol, 32: 4453.. Together, these studies underscore the growing impact of liquid biopsy and ctDNA analysis in expanding the reach of cancer diagnosis and improving risk stratification for metastatic progression."
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