Chapter

Radiopharmaceutical Therapy

From Future of Cancer Science | AACR Cancer Progress Report 2025 by Sambif

Concepts

1. RLT Basics

   "Radiopharmaceutical therapies, including radioligand therapies (RLTs), are a rapidly evolving class of cancer therapeutics that use radioactive compounds to deliver cytotoxic radiation directly to ca

2. Clinical Innovation

   "The effectiveness of these therapies has brought about a wave of innovation and clinical exploration. The success of Pluvicto in targeting prostate-specific membrane antigen (PSMA)–expressing prostat

3. Emerging Delivery

   "Emerging technologies are further expanding the potential of radiopharmaceuticals by refining delivery methods and exploring novel isotopes. In a first-in-human trial for glioblastoma, instead of usi