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Cancer Development

Cancer Development (Health Education · Cancer) — "Cancer is caused by changes to genes that control the way our cells function, especially how they grow and di…

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  • Cancer results from genetic changes that alter cell growth and division, and it can spread through metastasis.
  • Cancer-causing genetic changes affect the genes that control how cells function, grow, and divide.
  • Some genetic changes are inherited from a person’s parents.
  • Other genetic changes arise during a person’s lifetime.
  • Lifetime changes can result from errors during cell division or DNA damage caused by environmental exposures.
  • Chemicals in tobacco smoke are cancer-causing environmental exposures.
  • Ultraviolet rays from the sun are cancer-causing radiation exposures.
  • Metastasis is the process by which cancer cells spread to other parts of the body.
  • Cancer cells can break away from the primary cancer and travel through the blood or lymph system.
  • The spreading cells can form new tumors, called metastatic tumors, in other parts of the body.
  • Metastatic cancer has the same name and the same type of cancer cells as the original primary cancer.
  • Breast cancer that spreads to the lung is metastatic breast cancer, not lung cancer.
  • Under a microscope, metastatic cancer cells generally look like cells from the original cancer.
  • Metastatic and original cancer cells usually share molecular features.
  • Shared molecular features can include specific chromosome changes.
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Cancer Development

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Health Education

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"Cancer is caused by changes to genes that control the way our cells function, especially how they grow and divide. Genetic changes that cause cancer can be inherited from our parents. They can also arise during a person’s lifetime as a result of errors that occur as cells divide or because of damage to DNA caused by certain environmental exposures. Cancer-causing environmental exposures include substances, such as the chemicals in tobacco smoke, and radiation, such as ultraviolet rays from the sun. In metastasis, cancer cells break away from where they first formed, called the primary cancer, travel through the blood or lymph system, and form new tumors, called metastatic tumors, in other parts of the body. The metastatic tumor is the same type of cancer as the primary tumor. A cancer that has spread from the place where it first started to another place in the body is called metastatic cancer. The process by which cancer cells spread to other parts of the body is called metastasis. Metastatic cancer has the same name and the same type of cancer cells as the original, or primary, cancer. For example, breast cancer that spreads to and forms a metastatic tumor in the lung is metastatic breast cancer, not lung cancer. Under a microscope, metastatic cancer cells generally look the same as cells of the original cancer. Moreover, metastatic cancer cells and cells of the original cancer usually have some molecular features in common, such as the presence of specific chromosome changes."

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