"One major difference between fat-soluble vitamins and water-soluble vitamins is the way they are absorbed in the body. Vitamins are absorbed primarily in the small intestine, and their bioavailability is dependent on the food composition of the diet. Fat-soluble vitamins are absorbed along with dietary fat. Therefore, if a meal is very low in fat, the absorption of the fat-soluble vitamins will be impaired. Once fat-soluble vitamins have been absorbed in the small intestine, they are packaged and incorporated into chylomicrons along with other fatty acids and transported in the lymphatic system to the liver. Water-soluble vitamins, on the other hand, are absorbed in the small intestine but are transported to the liver through blood vessels."