"HIPEC is a new colorectal cancer treatment procedure that combines open cytoreductive surgery (CRS) with further administration of heated chemotherapy into the abdominal cavity. This treatment is used mainly for patients with metastatic peritoneal cancer. The procedure starts with the surgical removal of visible tumors. Then, the circulation of warmed chemotherapeutic agents is performed within the peritoneal cavity. The heat allows for better penetration of the chemotherapy and, by that, increases its effectiveness. Thanks to the procedure, the microscopic cancer cells that are left after the surgery are being destroyed."