Bifalgorithm post · BMJ Open Diabetes Research & Care is an open access · Cohort definition and data collection
Eligibility Criteria
Eligibility Criteria (BMJ Open Diabetes Research & Care is an open access · Cohort definition and data collection) — "Women were included in the study if they…
Ideas in this flowchart
- Study population and data-selection framework for women with GDM
- Inclusion criteria
- Diagnosis of GDM based on the UK National Institute for Health and Care Excellence criteria
- Complete OGTT baseline and 120-minute glucose data
- Management using basal insulin
- Pregnancy and diabetes-related exclusions
- Pre-existing diabetes or later diagnosis of an alternative form of diabetes
- Non-singleton pregnancies
- Insulin protocol and record-quality exclusions
- Nonadherence to insulin titration or failure to record three consecutive target fasting blood sugars
- Significant gaps preventing reliable determination of basal insulin levels at target achievement
- Patients with partial missing data were retained when sufficient information supported key outcome determination
- Retained outcomes included time to achieve target fasting glucose and insulin dose requirements
- The approach maximized clinically meaningful data while maintaining outcome validity and interpretability