"https://doi.org/10.1038/s42003-026-10789-6 Received: 4 October 2025 Accepted: 6 August 2026 Cite this article as: Kong, W.-L., Chang, Y.-H., Chen, W.-N. et al. Unraveling the immune landscape and molecular signatures of antibody-dependent cellular cytotoxicity in SARS-CoV-2 clearance. Commun Biol (2026). https://doi.org/ 10.1038/s42003-026-10789-6 Wye-Lup Kong, Yi-Hsuan Chang, Wei-Nan Chen, Yi-Fu Wang, Dong-Yen Tsai, Wen-Yu Chen, Fang-Ju Chang, I-Ying Lin, Ming-Tsan Liu, Wan-Chen Hsieh, Yi-Hua Chen, Yi-Shiuan Tzeng, Szu-Teng Ma, Kai Xuan Tin, Chih-Heng Huang, Chun-Che Liao, Jian-Jong Liang, Yu-Chi Chou, An-Yu Chen, Jia-Tsrong Jan, Yen-Chen Chen, Deepa Sridharan, Takashi Angata, Yi-Ling Lin, Shih-Yu Chen, Mei-Yeh Jade Lu & Kuo-I Lin. We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply. If this paper is publishing under a Transparent Peer Review model then Peer Review reports will publish with the final article."