Bifalgorithm post · Latest research covid · ARTICLE IN PRESS
Immune Response
Immune Response (Latest research covid · ARTICLE IN PRESS) — "Antibodies produced by plasma cells from the activation of naïve or memory B cells in response to…
Ideas in this flowchart
- Antibody and Tfh-cell responses are central to immunity against SARS-CoV-2.
- Plasma cells produce antibodies after naïve or memory B-cell activation.
- B-cell activation occurs in response to SARS-CoV-2 infection or vaccination.
- Antibodies recognize, neutralize, and prevent the spread of the virus.
- T-follicular helper (Tfh) cells promote the generation of germinal centers.
- Germinal centers support antibody affinity maturation.
- Germinal centers generate memory B cells and plasma cells.
- In COVID-19-convalescent individuals, circulating S protein-specific Tfh-cell frequency positively correlates with neutralizing antibody titers.
