Bifalgorithm post · Latest research covid · ARTICLE IN PRESS
Antiviral Activity
Antiviral Activity (Latest research covid · ARTICLE IN PRESS) — "Antibody-mediated antiviral activity is primarily affected through two distinct mechanisms: ne…
Ideas in this flowchart
- Antibody-mediated antiviral activity
- Neutralization is one of two distinct mechanisms.
- Neutralization prevents interactions between viral surface proteins and host cell receptors, directly inhibiting viral entry.
- Fc domain-mediated effector functions are the second mechanism.
- Fc domain-mediated functions engage immune effector cells to eliminate infected cells.
- Complement-dependent cytotoxicity (CDC)
- Antibody-dependent cellular phagocytosis (ADCP)
- Antibody-dependent cellular cytotoxicity