Ideas in this flowchart

• 2024 findings on depressive symptoms and PCFS grades
• Depressive symptoms were associated with several functional and physical symptoms
• Functional limitation showed the largest association (aOR, 8.02; 95% CI 3.20–20.05)
• Rash was associated with depressive symptoms (aOR, 6.43; 95% CI 1.73–23.90)
• Headache was associated with depressive symptoms (aOR, 5.03; 95% CI 1.95–13.08)
• Fatigue was associated with depressive symptoms (aOR, 4.98; 95% CI 1.76–14.00)
• Concentration difficulties were associated with depressive symptoms (aOR, 4.41; 95% CI 1.93–10.03)
• Resting dyspnea was associated with depressive symptoms (aOR, 4.36; 95% CI 1.36–13.90)
• Joint pain was associated with depressive symptoms (aOR, 3.73; 95% CI 1.72–8.07)
• BMI ≥ 30 kg/m2 was associated with higher PCFS grades (aOR, 2.84; 95% CI 1.25–6.44)
• Hypertension, anxiety, and sleep difficulties were not retained in the final model
• The associations were reported in Table 2