Bifalgorithm post

Lp Little A, ldl's weird cousin. The tail on the LP Little A that makes your blood clo more easily is nearly the whole story. Part two of the LP Little A series. What makes this particle biologically different from regular LDL. Ldl particles are little spheres that ferry fat and cholesterol through your blood. Lp Little A is built on that same LDL scaffold, but with one addition, an extra protein tail called apolipoprotein Little A coated by the LPA gene hooked on LDL with a chemical bond. That tail does two things that are worth noting. First, it seems to make blood more prone to clouding, which may have helped our ancestors survive injuries or blood loss, but isn't exactly a feature you want later in life when it comes to your arteries. Second, the length of that tail matters a whole lot. Shorter tails are linked to higher LP Little A levels in the blood because longertailed particles tend to get broken down in the liver before they're released. Bottom line lp Little A isn't just extra LDL, it's a structurally different particle with its own risk profile. Stay tuned for more.

Lp Little A, ldl's weird cousin. The tail on the LP Little A that makes your blood clo more easily is nearly the whole story. Part two of the LP Little A serie…