Concept

Model Findings

Factors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports / Factors associated with post-COVID condition (phase I, 2021)

"In organ system-specific models, 23 acute-phase symptoms across multiple organ systems remained associated with PCC (Supplementary Table S7b).\n\nIn the final multivariable model (Table 1), older age ≥ 50 years (adjusted odds ratio [aOR] 1.62; 95% CI 1.18–2.21) and obesity (aOR, 1.64; 95% CI 1.07–2.50) were associated with a higher risk of PCC. Among acute-phase symptoms, fatigue (aOR, 1.81; 95% CI 1.29–2.67), memory difficulties (aOR, 5.80; 95% CI 3.10–10.97), concentration difficulties (aOR, 1.73; 95% CI 1.19–2.52), chest tightness (aOR, 1.93; 95% CI 1.12–3.32), dyspnea (aOR, 1.76; 95% CI 1.10–2.83), olfactory dysfunction (aOR, 2.03; 95% CI 1.51–2.75), numbness or paresthesia (aOR, 4.71; 95% CI 1.34–16.56), palpitations (aOR, 2.18; 95% CI 1.27–3.77), anxiety disorder (aOR, 2.28; 95% CI 1.03–5.01) and depressive symptoms (aOR, 4.96; 95% CI 1.03–23.90) remained associated with PCC after adjustment for sex, age group and obesity. The aOR estimate for numbness or paresthesia was based on small number of exposure counts and was therefore imprecise.\n\nTable 1 Final Multivariable Logistic Regression Models of Factors Associated With Post-COVID-19 Condition (PCC), Phases I, II and Persistent PCC (2021–2024)."

Related Ideas

  • Primary ModelFactors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports · Factors associated with post-COVID condition (phase II, 2024)
  • Variable SelectionFactors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports · Statistical analysis
  • Model ComparisonFactors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports · Factors associated with post-COVID condition (phase II, 2024)
  • Sensitivity AnalysesFactors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports · Factors associated with post-COVID condition (phase II, 2024)
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  • Persistent PCCFactors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports · Statistical analysis
  • Age AssociationFactors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports · Factors associated with persistent PCC (2021–2024)
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Model Findings | Factors associated with persistent post-COVID-19 condition and functional limitation four years after SARS-CoV-2 infection | Scientific Reports | Bifalgorithm | Bifalgorithm