Chapter

Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

From Nature by Sambif

Concepts

  1. Myeloid Agonist

    "A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells."

Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism | Nature | Bifalgorithm | Bifalgorithm