Chapter
Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism
From Nature by Sambif
Concepts
- Myeloid Agonist
"A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells."