Concept

Myeloid Agonist

Nature / Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism

"A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells."

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Myeloid Agonist | Nature | Bifalgorithm | Bifalgorithm