Concept
Myeloid Agonist
Nature / Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism
"A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells."
Related Ideas
- Il-10 AgonismNature · Global conservation area coverage substantially exceeds current estimates