Concept
Brain Organoids
Future of Cancer Science | AACR Cancer Progress Report 2025 / Basic Research Discoveries
"In another study, researchers used CRISPR to introduce cancer-driving mutations in experimental human brain organoids (see Sidebar 6), which retain the structural complexity of the developing brain. These organoids provide a powerful platform for studying brain tumor development and can be used to investigate the specific roles of individual gene variants (1068)Pagliaro A, et al. (2025) Nat Protoc.. Advances in basic research using CRISPR technologies will continue to enable the development of more biologically relevant experimental models and deepen insights into cancer biology."
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