Targeted Delivery

"At the same time, researchers are also developing advanced delivery systems that send CRISPR directly to tumors. For example, researchers have recently developed nanoparticles that cross the blood–brain barrier, a protective layer of tightly packed cells that protects the brain from harmful substances, and activate gene editing only within glioblastoma tumor cells (1078)Li Q, et al. (2025) ACS Appl Mater Interfaces, 17: 4480.. In another study, an EGFR-targeted nanoparticle was developed that delivers CRISPR to head and neck cancers, resulting in complete disappearance of tumors in some animal models (1079)Masarwy R, et al. (2025) Adv Sci (Weinh), 12: e2411032.."