Concept
Regression Models
Association between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care / Statistical analysis
"Continuous variables were summarized using means and SD. Categorical variables were summarized using counts and percentages. Multivariable linear regression was used to assess associations between baseline characteristics (fasting OGTT result, 120-minute OGTT result, maternal age, and pre-pregnancy weight or pre-pregnancy BMI), and insulin requirements. Separate models were constructed for initial insulin requirement and peak insulin requirement as defined above. For each outcome, separate models were built with either pre-pregnancy weight or BMI given the collinearity between the two measures. Regression coefficients (β), 95% CIs, and p values were reported. Model assumptions were assessed visually using residual plots. R-squared was used to evaluate the proportion of variation in the outcome variable that the models explain, thereby assessing the model’s explanatory power. To compare relative variable importance, models were re-run with standardization of all continuous variables."
Related Ideas
- Regression ModelsAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Results
- Insulin RequirementsAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Definitions of study outcomes
- Clinical VariablesAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Cohort definition and data collection
- Insulin RequirementsAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · What this study adds
- Dose PredictionAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Comparison with previous literature
- Study LimitationsAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Strengths and limitations
- Prior ResearchAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Comparison with previous literature
- Insulin DosingAssociation between weight/body mass index and insulin dose requirements in gestational diabetes: a retrospective cohort study | BMJ Open Diabetes Research & Care · Implications for clinical practice and future research